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Kisspeptin-10 versus kisspeptin-54

Reproductive and sexual neuroscience without conflating indications. What should I know about kisspeptin-10 versus kisspeptin-54?

In the women’s HSDD crossover trial,32 women completed both visits involving acute IV kisspeptin 54 or placebo and neuroimaging measurements.

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Record 01

Effects of Kisspeptin Administration in Women With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial. ↗

Record 02

Effects of Kisspeptin on Sexual Brain Processing and Penile Tumescence in Men With Hypoactive Sexual Desire Disorder: A Randomized Clinical Trial. ↗

Record 03

Kisspeptin-54 triggers egg maturation in women undergoing in vitro fertilization. ↗

Record 04

Certain Bulk Drug Substances for Use in Compounding that May Present Significant Safety Risks ↗

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In the women’s HSDD crossover trial,32 women completed both visits involving acute IV kisspeptin 54 or placebo and neuroimaging measurements.

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The women’s study found changes in sexual/attraction brain processing, rather than demonstrating a durable cure for HSDD.

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In the men’s HSDD crossover trial,32 men completed both visits; acute IV kisspeptin 54 changed neural processing and some secondary physiological/behavioral measures.

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The 2014 IVF study administered subcutaneous kisspeptin 54 to 53 women after controlled ovarian stimulation; mature eggs and subsequent pregnancies were observed.

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